Acromegaly – Diagnosis and Clinical Management

Clinical Manifestations and Diagnosis of Acromegaly

Acromegaly and gigantism are due to excess GH production, usually as a result of a pituitary adenoma. The incidence of acromegaly is 5 cases per million per year and the prevalence is 60 cases per million. Clinical manifestations in each patient depend on the levels of GH and IGF-I, age, tumor size, and the delay in diagnosis. Manifestations of acromegaly are varied and include acral and soft t...

Diagnosis and management of acromegaly: giant invasive adenoma.

Acromegaly is a rare disorder caused by excessive growth hormone. Majority of acromegaly are due to pituitary adenoma. It is estimated that 5% of pituitary adenoma become invasive and may grow to gigantic sizes (>4 cm in diameter). We would like to describe a man with giant invasive adenoma. We describe the case of 52-year-old man with acromegaly. The patient was presented to medical care becau...

Diagnosis and Management of Acromegaly in 2014 ( Update from 2012 )

Acromegaly is an uncommon disorder that, in the vast majority of cases, is the result of a growth hormone (GH)-secreting pituitary adenoma. Because tumors are often macroadenomas at the time of diagnosis, there may be a number of signs and symptoms related to local mass effects, including headache, visual field loss, ophthalmoplegia, and hypopituitarism. Chronic GH and insulin-like growth facto...

[Laboratory diagnosis of acromegaly].

Management of acromegaly

was an accidental observation when the patient went to the doctor for some other condition. Surprisingly, less than 10% of the patients went actually complaining of a change in their appearance, but this reflects the very slow way in which the condition usually evolves. Most of the other presenting symptoms were due to local spread of the tumour or to recognised features or complications of acr...